Chp2 Antikörper (Internal Region)

Produktnummer ABIN6258442

Dieser Anti-Chp2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Chp2 in WB, IF, ELISA, ICC und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Chp2 Antikörper (Internal Region) (ABIN6258442)

Target: Chp2

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chp2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Produktdetails anti-Chp2 Antikörper

Bindungsspezifität: Internal Region

Spezifität: CHP2 Antibody detects endogenous levels of total CHP2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CHP2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Chp2

Target: Chp2

Hintergrund:

Description: Functions as an integral cofactor in cell  pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing  pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

Gene: CHP2

Molekulargewicht: 22 kDa

Gen-ID: 63928

UniProt: O43745